R version 4.5.2 (2025-10-31 ucrt)
Platform: x86_64-w64-mingw32/x64
Running under: Windows 10 x64 (build 19045)

Matrix products: default
  LAPACK version 3.12.1

locale:
[1] LC_COLLATE=Chinese (Simplified)_China.utf8 
[2] LC_CTYPE=Chinese (Simplified)_China.utf8   
[3] LC_MONETARY=Chinese (Simplified)_China.utf8
[4] LC_NUMERIC=C                               
[5] LC_TIME=Chinese (Simplified)_China.utf8    

time zone: Asia/Shanghai
tzcode source: internal

attached base packages:
[1] stats4    stats     graphics  grDevices utils     datasets  methods  
[8] base     

other attached packages:
 [1] circlize_0.4.18             GO.db_3.22.0               
 [3] org.Hs.eg.db_3.22.0         AnnotationDbi_1.72.0       
 [5] clusterProfiler_4.18.4      DESeq2_1.50.2              
 [7] SummarizedExperiment_1.40.0 Biobase_2.70.0             
 [9] MatrixGenerics_1.22.0       matrixStats_1.5.0          
[11] GenomicRanges_1.62.1        Seqinfo_1.0.0              
[13] IRanges_2.44.0              S4Vectors_0.48.1           
[15] BiocGenerics_0.56.0         generics_0.1.4             
[17] jsonlite_2.0.0             

loaded via a namespace (and not attached):
  [1] DBI_1.3.0               gson_0.2.2              rlang_1.3.0            
  [4] magrittr_2.0.5          DOSE_4.4.0              otel_0.2.0             
  [7] compiler_4.5.2          RSQLite_3.53.3          systemfonts_1.3.2      
 [10] png_0.1-9               vctrs_0.7.3             reshape2_1.4.5         
 [13] stringr_1.6.0           shape_1.4.6.1           pkgconfig_2.0.3        
 [16] crayon_1.5.3            fastmap_1.2.0           XVector_0.50.0         
 [19] enrichplot_1.30.5       ragg_1.5.2              purrr_1.2.2            
 [22] bit_4.6.0               cachem_1.1.0            aplot_0.3.2            
 [25] blob_1.3.0              tidydr_0.0.7            DelayedArray_0.36.1    
 [28] tweenr_2.0.3            BiocParallel_1.44.0     cluster_2.1.8.1        
 [31] parallel_4.5.2          R6_2.6.1                stringi_1.8.9          
 [34] RColorBrewer_1.1-3      GOSemSim_2.36.0         Rcpp_1.1.2             
 [37] ggtangle_0.1.4          R.utils_2.13.0          Matrix_1.7-4           
 [40] splines_4.5.2           igraph_2.3.4            tidyselect_1.2.1       
 [43] qvalue_2.42.0           abind_1.4-8             codetools_0.2-20       
 [46] lattice_0.22-7          tibble_3.3.1            plyr_1.8.9             
 [49] withr_3.0.3             treeio_1.34.0           KEGGREST_1.50.0        
 [52] S7_0.2.2                gridGraphics_0.5-1      polyclip_1.10-7        
 [55] scatterpie_0.2.6        Biostrings_2.78.0       pillar_1.11.1          
 [58] ggtree_4.0.5            ggfun_0.2.2             ggplot2_4.0.3          
 [61] scales_1.4.0            tidytree_0.4.8          glue_1.8.1             
 [64] gdtools_0.5.2           lazyeval_0.2.3          tools_4.5.2            
 [67] ggnewscale_0.5.2        data.table_1.18.6.1     fgsea_1.36.2           
 [70] locfit_1.5-9.12         ggiraph_0.9.6           fs_2.1.0               
 [73] fastmatch_1.1-8         cowplot_1.2.0           grid_4.5.2             
 [76] tidyr_1.3.2             ape_5.8-1               colorspace_2.1-4       
 [79] nlme_3.1-168            patchwork_1.3.2         ggforce_0.5.0          
 [82] cli_3.6.6               rappdirs_0.3.4          textshaping_1.0.5      
 [85] fontBitstreamVera_0.1.1 S4Arrays_1.10.1         svglite_2.2.2          
 [88] dplyr_1.2.1             gtable_0.3.6            R.methodsS3_1.8.2      
 [91] yulab.utils_0.2.5       digest_0.6.39           fontquiver_0.2.1       
 [94] SparseArray_1.10.10     ggrepel_0.9.8           ggplotify_0.1.4        
 [97] htmlwidgets_1.6.4       farver_2.1.2            htmltools_0.5.9        
[100] memoise_2.0.1           R.oo_1.27.1             lifecycle_1.0.5        
[103] httr_1.4.9              GlobalOptions_0.1.4     fontLiberation_0.1.0   
[106] bit64_4.8.6             MASS_7.3-65            
